5-HTP is an amino acid which occurs naturally. It is sold in many countries including the United States not only as a diet supplement but also as an appetite suppressant, antidepressant and to abet sleep. 5 –HPT affects the serotonin synthesis present in the central nervous system and causes psychoactiveness. 5 – HPT is believed to increase the production of neurons in the serotonin; this in turn increases serotonin release and causes mood imrpovement. When administered along with decarboxylase inhibitor like carbidopa it increases the level of plasma. Nevertheless, several studies have come up with contradictory reports. While some has come up with theories about its effectiveness even in the absence of decarboxylase inhibitor, others indicate that 5 – HPT when combined with carbidopa could cause conditions similar to scleroderma.

Inositol works as a second messenger within our bodies to stimulate the release of calcium from its storage place within our bodies; it allows the transmission of neural signals to be enhanced.

Passion Flower- Passion vines, or Passiflora, are a 500 species strong genus of flowering plants that all belong to the family of Passifloraceae. While most of the plants are classified as vines, there are also some shrubs and herbaceous plants that can be found. With the exception of Europe and Africa, as well as Antarctica, these plants are found all over the rest of the world. While the passion flower is mostly known for the Maracuja, or Passiflora edulis, the passion fruit, the vines of some species in this genus are known to have properties that have been used by Native Americans for treatment of insomnia, epilepsy and hysteria, as noted with Passiflora incarnata. Many other species contain beta carboline harmala alkaloids, which function as monoamine oxidase inhibitors and are powerful antidepressants.

Valerian Root is a perennial plant, which can bloom into pink and white flowers that have a scent perceived as sweetly. It can be found in Europe and some areas in Asia, recently also in North America, where it has been imported. The sedative and anxiolytic properties of the valerian roots have been known to mankind for centuries. Valerian root extracts contain many pharmacologically active substances, some which are valeric acid, GABA, isovaleramide, valerine, valerianine, actinidine, an essential oil that contains sesquiterpenes, and many more. Since that valerian has been used as a pain reliever, anti convulsant, a sedative and for migraine treatment, the primary use has been always related to the GABA receptor system. It has been recommended as a potent sleeping agent.